Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 9/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909676 | 0.89 | SYK (0.45) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL14909675 | 0.89 | SYK (0.45) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL20473551 | 0.88 | PDE4B (0.46) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL14909803 | 0.88 | PDE4B (0.46) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL14909754 | 0.88 | PDE4B (0.46) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL5027993 | 0.86 | SYK (0.50) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL9106928 | 0.86 | SYK (0.50) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL14909666 | 0.85 | SYK (0.42) | PDE4BSYKHTTMAPTMEN1 | |
| SCHEMBL14909118 | 0.85 | PDE4B (0.48) | PDE4BSYKHTTMAPTCYP1A2 | |
| SCHEMBL16164337 | 0.83 | SYK (0.48) | PDE4BSYKHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |