Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065460 | 0.77 | EPHX1 (0.34) | EPHX1CRBNTAS2R38 | |
| SCHEMBL15293407 | 0.71 | CRBN (0.45) | EPHX1CRBNTAS2R38KDM4ECA2 | |
| SCHEMBL13381239 | 0.71 | — | — | |
| SCHEMBL11120574 | 0.71 | — | — | |
| SCHEMBL11120572 | 0.71 | — | — | |
| SCHEMBL25051914 | 0.67 | — | — | |
| SCHEMBL11093680 | 0.67 | — | — | |
| SCHEMBL11093673 | 0.67 | — | — | |
| SCHEMBL11093842 | 0.67 | — | — | |
| SCHEMBL22811 | 0.67 | GRIK1 (0.39) | PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046219-A1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | ASTRAZENECA AB (SE) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046219-A1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | MC4R, MC3R, MC5R | EPHX1 4172/4885CRBN 2530/4885TAS2R38 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.