Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21514826 | 1.00 | GBA1 (0.31) | GBA1CYP1A2TDP1 | |
| SCHEMBL21515903 | 1.00 | GBA1 (0.31) | GBA1CYP1A2TDP1 | |
| SCHEMBL204261 | 0.84 | TDP1 (0.36) | GBA1TDP1 | |
| SCHEMBL4648895 | 0.84 | TDP1 (0.36) | GBA1TDP1 | |
| SCHEMBL5076199 | 0.84 | TDP1 (0.36) | GBA1TDP1 | |
| SCHEMBL4895931 | 0.84 | TDP1 (0.36) | GBA1TDP1 | |
| SCHEMBL17795772 | 0.84 | TDP1 (0.36) | GBA1TDP1 | |
| Hydrochloric Acid SCHEMBL143429 | 0.82 | TDP1 (0.39) | GBA1TDP1 | |
| SCHEMBL16845501 | 0.80 | SMN1; SMN2 (0.35) | GBA1 | |
| SCHEMBL26431341 | 0.80 | GBA1 (0.30) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146786-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-9365612-B2 | Caspase inhibitors | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-06-14 | — | — | US | disclosed |
| EP-2468744-A2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-27 | — | — | EP | disclosed |