Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231642 | 0.82 | CHRM3 (0.47) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL231643 | 0.82 | CHRM3 (0.47) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL880930 | 0.81 | CHRM3 (0.59) | CHRM2CHRM3CHRM1 | |
| SCHEMBL10076905 | 0.79 | CHRM3 (0.40) | CHRM2CHRM3CHRM1 | |
| SCHEMBL10077722 | 0.78 | CHRM3 (0.38) | CHRM2CHRM3CHRM1POLBMAPT | |
| SCHEMBL880941 | 0.77 | CHRM3 (0.40) | CHRM2CHRM3CHRM1 | |
| SCHEMBL5685475 | 0.70 | MAPT (0.55) | POLBMAPTMAPK1 | |
| SCHEMBL10256911 | 0.69 | CHRM2 (0.64) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL12014464 | 0.68 | CHRM2 (0.53) | CHRM2CHRM3CHRM1CYP2D6CHRM4 | |
| SCHEMBL13240866 | 0.68 | CHRM2 (0.53) | CHRM2CHRM3CHRM1CYP2D6CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313404-B1 | QUINUCLIDINE CARBONATE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2012-03-28 | — | — | EP | disclosed |