Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222703 | 1.00 | KCNH2 (0.42) | KCNH2HTR1ATRPV1USP30 | |
| SCHEMBL1223089 | 1.00 | KCNH2 (0.42) | KCNH2HTR1ATRPV1USP30 | |
| SCHEMBL1223019 | 0.90 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL1222722 | 0.90 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL1222721 | 0.90 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL1224569 | 0.89 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL1224571 | 0.89 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL1224606 | 0.88 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL1224481 | 0.88 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL1222597 | 0.88 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217029-B2 | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-10 | — | — | US | claimed |