Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | TP53 | P04637 | 6/20 | 0.73 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005497 | 0.94 | MAPT (0.73) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1007923 | 0.93 | MAPT (0.74) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1062417 | 0.92 | MAPT (0.73) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL12674202 | 0.91 | MAPT (0.60) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1008381 | 0.91 | MAPT (0.71) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1008098 | 0.90 | MAPT (0.73) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL8004294 | 0.90 | MAPT (0.70) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1009574 | 0.89 | MAPT (0.71) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1006830 | 0.89 | MAPT (0.71) | MAPTTP53POLBTSHRGAA | |
| SCHEMBL1007887 | 0.89 | MAPT (0.73) | MAPTTP53POLBTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |