SCHEMBL10079949

SCHEMBL10079949

Oc1cccc(CN(c2ccccc2)n2cnnc2)c1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 20/20 0.72
STS P08842 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14549043 0.87 CYP19A1 (0.71) CYP19A1STS
SCHEMBL2060143 0.84 CYP19A1 (1.00) CYP19A1
SCHEMBL10062722 0.82 CYP19A1 (0.58) CYP19A1STS
SCHEMBL13292479 0.78 CYP19A1 (0.64) CYP19A1STS
SCHEMBL8446304 0.71 CYP19A1 (0.75) CYP19A1STS
SCHEMBL12171637 0.71 CYP19A1 (0.58) CYP19A1STS
SCHEMBL14548949 0.70 CYP19A1 (0.50) CYP19A1STS
SCHEMBL8446068 0.69 CYP19A1 (0.76) CYP19A1
SCHEMBL12171667 0.68 CYP19A1 (0.48) CYP19A1STS
SCHEMBL12171652 0.68 CYP19A1 (0.48) CYP19A1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148415-B2 Sulfamic acid ester compounds useful in the inhibition of steroid sulphatase activity and aromatase activity STERIX LIMITED (GB) 2012-04-03 US disclosed