⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750082 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8046759 | 0.79 | — | — | |
| Fluoride Ion SCHEMBL11599607 | 0.77 | — | — | |
| SCHEMBL827664 | 0.74 | — | — | |
| SCHEMBL8400154 | 0.72 | KDM4E (0.37) | — | |
| Dipyridyl SCHEMBL16026539 | 0.71 | KDM4E (0.93) | — | |
| Dipyridyl SCHEMBL4196776 | 0.69 | KDM4E (0.88) | — | |
| Dipyridyl SCHEMBL29351528 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL3711450 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL29907716 | 0.67 | KDM4E (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714244-B2 | Substituted pyrido[4,3-d]pyrimidines as Wee-1 inhibitors | ALMAC DISCOVERY LIMITED (GB) | 2017-07-25 | — | — | US | disclosed |
| US-9434698-B2 | Process for preparing antiviral compounds | ABBVIE INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-20160158377-A1 | BCL-XL Inhibitory Compounds and Antibody Drug Conjugates Including the Same | ABBVIE INC. (US) | 2016-06-09 | — | — | US | disclosed |
| US-9345702-B2 | Methods of treatment using selective Bcl-2 inhibitors | ABBVIE INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20160060258-A1 | 2-AMINOPYRIDO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND THEIR USE AS WEE-1 INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2016-03-03 | — | — | US | disclosed |
| US-9095590-B2 | Anti-infective agents and uses thereof | ABBVIE INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150191437-A1 | PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS | ABBVIE INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20150150870-A1 | METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS | ABBVIE INC. | 2015-06-04 | — | — | US | disclosed |
| US-8980643-B2 | Dicationic liquid salts and methods of use thereof | SIGMA-ALDRICH CO., LLC (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140171429-A1 | BICYCLIC INHIBITORS OF ALK | ABBVIE INC. (US) | 2014-06-19 | — | — | US | disclosed |
| EP-2105787-B1 | DISPLAY ELEMENT AND DRIVING METHOD THEREOF | KONICA MINOLTA HOLDINGS INC (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-8435980-B2 | Pyrrolopyridine inhibitors of kinases | ABBVIE INC. (US) | 2013-05-07 | — | — | US | disclosed |
| US-8426408-B2 | Pyrimidine inhibitors of kinases | ABBVIE INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120122924-A1 | NAMPT INHIBITORS | ABBOTT LABORATORIES (US) | 2012-05-17 | — | — | US | disclosed |
| US-8064119-B2 | Display element and driving method thereof | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-11-22 | — | — | US | disclosed |
| US-20110058244-A1 | ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110017908-A1 | DICATIONIC LIQUID SALTS AND METHODS OF USE THEREOF | SIGMA-ALDRICH CO. (US) | 2011-01-27 | — | — | US | disclosed |
| US-20110015173-A1 | PYRROLOPYRIDINE INHIBITORS OF KINASES | ABBOTT LABORATORIES (US) | 2011-01-20 | — | — | US | disclosed |
| US-20100091352-A1 | DISPLAY ELEMENT AND DRIVING METHOD THEREOF | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-2105787-A1 | DISPLAY ELEMENT AND METHOD FOR DRIVING DISPLAY ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2009-09-30 | — | — | EP | disclosed |