Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PTPRA | P18433 | 1/20 | 0.65 |
| ▸ | PTPRB | P23467 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pontacyl Violet 6R SCHEMBL12282563 | 1.00 | CYP1A2 (1.00) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| Pontacyl Violet 6R SCHEMBL29412925 | 1.00 | CYP1A2 (1.00) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL60352 | 0.89 | CYP1A2 (0.80) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL60351 | 0.89 | CYP1A2 (0.80) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL29767885 | 0.89 | CYP1A2 (0.80) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL11227186 | 0.89 | CYP1A2 (0.80) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL11227192 | 0.89 | CYP1A2 (0.80) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL15181277 | 0.89 | CYP1A2 (0.79) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL11763985 | 0.87 | CYP1A2 (0.79) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 | |
| SCHEMBL70833 | 0.86 | CYP1A2 (0.76) | CYP1A2MAPK1CYP2C9DNASE1L3PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | CYP1A2 4401/4885MAPK1 2957/4885CYP2C9 4838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.