Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625962 | 0.85 | CYP3A4 (0.57) | CYP3A4ABL1 | |
| SCHEMBL15188916 | 0.72 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL15168607 | 0.72 | CRBN (0.42) | CYP3A4ABL1 | |
| SCHEMBL1703305 | 0.70 | CYP3A4 (0.57) | CYP3A4ABL1 | |
| SCHEMBL1703309 | 0.70 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL1702817 | 0.67 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL1702845 | 0.67 | CYP3A4 (0.39) | CYP3A4ABL1 | |
| SCHEMBL1702764 | 0.67 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL15168201 | 0.66 | CRBN (0.38) | CYP3A4ABL1 | |
| SCHEMBL1702611 | 0.66 | CYP3A4 (0.39) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020037-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-02-16 | — | — | WO | disclosed |