Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060029 | 0.94 | TLR7 (0.74) | TLR7 | |
| SCHEMBL1009605 | 0.90 | TLR7 (0.77) | TLR7 | |
| SCHEMBL1061173 | 0.90 | TLR7 (0.77) | TLR7 | |
| SCHEMBL1006099 | 0.89 | TLR7 (0.76) | TLR7 | |
| SCHEMBL16996998 | 0.89 | TLR7 (0.75) | TLR7 | |
| SCHEMBL18598565 | 0.89 | TLR7 (0.75) | TLR7 | |
| SCHEMBL17001190 | 0.89 | TLR7 (0.75) | TLR7 | |
| SCHEMBL18598573 | 0.89 | TLR7 (0.75) | TLR7 | |
| SCHEMBL1060581 | 0.88 | TLR7 (0.72) | TLR7 | |
| SCHEMBL12723400 | 0.88 | TLR7 (0.77) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2011-01-05 | — | — | EP | claimed |
| WO-2009111337-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2009-09-11 | — | — | WO | claimed |
| EP-2459216-B1 | IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2013-10-30 | — | — | EP | disclosed |
| EP-2558069-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | Novartis AG (CH) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011130379-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | NOVARTIS AG (CH) | 2011-10-20 | — | — | WO | disclosed |