Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585553 | 0.97 | TSHR (0.41) | GPBAR1DHODHPPARGPPARATSHR | |
| SCHEMBL585409 | 0.97 | TSHR (0.41) | GPBAR1DHODHPPARGPPARATSHR | |
| SCHEMBL12057429 | 0.92 | NR5A1 (0.44) | TERTTOP1 | |
| SCHEMBL584884 | 0.91 | TSHR (0.47) | GPBAR1PPARGPPARATSHRALOX5 | |
| SCHEMBL12668273 | 0.87 | TSHR (0.41) | GPBAR1DHODHTSHRALOX5TERT | |
| SCHEMBL12057410 | 0.87 | STAT3 (0.47) | GPBAR1PPARGPPARATSHRALOX5 | |
| SCHEMBL6843058 | 0.86 | CYP1A2 (0.48) | GPBAR1DHODHTSHRTERTCYSLTR2 | |
| SCHEMBL19718136 | 0.85 | PPARG (0.51) | PPARGPPARACYSLTR2CYSLTR1HDAC3 | |
| SCHEMBL29831938 | 0.85 | PPARG (0.51) | PPARGPPARACYSLTR2CYSLTR1HDAC3 | |
| SCHEMBL14806865 | 0.85 | TSHR (0.41) | GPBAR1PPARGPPARATSHRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768666-B1 | NOVEL USES OF PORPHYRIN COMPOUNDS | DESTINY PHARMA LTD (GB) | 2012-02-15 | — | — | EP | disclosed |