Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.79 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.79 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.79 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.79 |
| ▸ | CASP7 | P55210 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | VDR | P11473 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.72 |
| ▸ | MDM4 | O15151 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999176 | 0.91 | GPBAR1 (0.65) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL23218026 | 0.90 | GPBAR1 (0.75) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL16728362 | 0.88 | GPBAR1 (0.73) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL22415770 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL22415902 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL22778334 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL24001452 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL24032585 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL24124431 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| Lagodeoxycholate SCHEMBL23781732 | 0.88 | GPBAR1 (1.00) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010516-A1 | GROWTH HORMONE CONJUGATES | NOVO NORDISK HEALTH CARE AG (CH) | 2012-01-26 | — | — | WO | disclosed |