SCHEMBL10086901

SCHEMBL10086901

CC(=O)C(C)C(C)(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13039773 0.75
SCHEMBL7587650 0.75
SCHEMBL12336186 0.75
SCHEMBL20098013 0.74 CA1 (0.30)
SCHEMBL14617059 0.73
SCHEMBL22485422 0.71
SCHEMBL15044679 0.71
SCHEMBL9720660 0.71
SCHEMBL19507003 0.69 CA12 (0.34)
SCHEMBL8473650 0.69 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018080-B2 Methods and compositions for treating cancer by targeting the CLEC2D-KLRB1 pathway THE BROAD INSTITUTE, INC. (US) 2024-06-25 US disclosed
US-20240018552-A1 NOVEL CRISPR ENZYMES AND SYSTEMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2024-01-18 US disclosed
US-10022455-B2 Biodegradable lipids for delivery of nucleic acids TRANSLATE BIO, INC. (US) 2018-07-17 US disclosed
US-20170281542-A1 LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2017-10-05 US disclosed
US-20170246319-A1 BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS SHIRE HUMAN GENETIC THERAPIES, INC. 2017-08-31 US disclosed
US-9663492-B2 Methods for the preparation of charged crosslinkers IMMUNOGEN, INC. (US) 2017-05-30 US disclosed
US-9629804-B2 Lipid formulations for delivery of messenger RNA SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2017-04-25 US disclosed
US-20160272616-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. 2016-09-22 US disclosed
US-9242936-B2 Methods for the preparation of charged crosslinkers IMMUNOGEN, INC. (US) 2016-01-26 US disclosed
US-20150166482-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. 2015-06-18 US disclosed
US-20150140070-A1 LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA TRANSLATE BIO, INC. 2015-05-21 US disclosed
US-8921566-B2 Methods for the preparation of charged crosslinkers IMMUNOGEN, INC. (US) 2014-12-30 US disclosed
US-20140135502-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. (US) 2014-05-15 US disclosed
US-20120165537-A1 METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS IMMUNOGEN, INC. (US) 2012-06-28 US disclosed