⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767053 | 0.96 | — | — | |
| SCHEMBL598322 | 0.78 | — | — | |
| SCHEMBL599341 | 0.78 | — | — | |
| SCHEMBL11810630 | 0.78 | EPHX2 (0.32) | — | |
| SCHEMBL282937 | 0.78 | — | — | |
| SCHEMBL23420992 | 0.78 | — | — | |
| SCHEMBL428437 | 0.78 | — | — | |
| SCHEMBL26675567 | 0.74 | — | — | |
| Water SCHEMBL28327000 | 0.74 | — | — | |
| SCHEMBL15264400 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828353-B1 | ISOINDOLO[2,1-A]QUINAZOLINE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2016-05-18 | — | — | EP | disclosed |
| US-9321902-B2 | Isoindolo[2, 1-A]quinazoline derivatives for stabilization of organic materials | BASF SE (DE) | 2016-04-26 | — | — | US | disclosed |
| US-20150087755-A1 | ISOINDOLO[2, 1-A]QUINAZOLINE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2015-03-26 | — | — | US | disclosed |
| EP-2828353-A1 | ISOINDOLO[2,1-A]QUINAZOLINE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2015-01-28 | — | — | EP | disclosed |
| US-8633245-B2 | PAI-1 inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2014-01-21 | — | — | US | disclosed |
| WO-2013139799-A1 | ISOINDOLO[2,1-A]QUINAZOLINE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2013-09-26 | — | — | WO | disclosed |
| EP-2272817-A1 | PAI-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20090312315-A1 | PAI-1 INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20070231654-A1 | Process of producing sulfonic group-containing substituted polyacetylene membrane, membrane obtained thereby and application thereof | EBARA CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |