⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350792 | 1.00 | — | — | |
| SCHEMBL22868293 | 0.70 | — | — | |
| SCHEMBL19050609 | 0.69 | — | — | |
| SCHEMBL7067051 | 0.67 | — | — | |
| SCHEMBL16976557 | 0.67 | — | — | |
| Nitrous Acid SCHEMBL4941623 | 0.67 | — | — | |
| SCHEMBL22710126 | 0.65 | — | — | |
| SCHEMBL28654382 | 0.65 | — | — | |
| SCHEMBL16078889 | 0.65 | — | — | |
| SCHEMBL23572364 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017068186-A9 | GITR AGONISTS | ABLYNX NV (BE) | 2017-06-22 | — | — | WO | disclosed |
| US-20160355608-A1 | HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS | XENCOR, INC. | 2016-12-08 | — | — | US | disclosed |
| US-9149542-B2 | Microvesicles derived from cell protoplast and use thereof | AEON MEDIX INC. (KR) | 2015-10-06 | — | — | US | disclosed |
| US-9084830-B2 | Microvesicles derived from cell protoplast and use thereof | AEON MEDIX INC. (KR) | 2015-07-21 | — | — | US | disclosed |
| US-20150174271-A1 | MICROVESICLES DERIVED FROM CELL PROTOPLAST AND USE THEREOF | AEON MEDIX INC. (KR) | 2015-06-25 | — | — | US | disclosed |
| EP-1778661-B1 | PROCESS FOR THE MANUFACTURE OF CHROMAN DERIVATIVES, ESPECIALLY ALPHA-TOCOPHEROL AND ALKANOATES THEREOF | DSM IP ASSETS BV (NL) | 2014-01-22 | — | — | EP | disclosed |
| US-20120020718-A1 | HEATING COSMETIC TREATMENT PROCESS USING A PARTICULAR POLYESTER | L'OREAL (FR) | 2012-01-26 | — | — | US | disclosed |