Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550891 | 0.81 | KMT2A (0.54) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL29444912 | 0.81 | KMT2A (0.58) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL22204537 | 0.81 | KMT2A (0.58) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL1226499 | 0.77 | NPC1 (0.49) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL29444424 | 0.77 | KMT2A (0.56) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL31461711 | 0.76 | MAPT (0.67) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL7457669 | 0.75 | KMT2A (0.62) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL10547080 | 0.75 | CHEK1 (0.49) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19374774 | 0.74 | NPC1 (0.68) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL10357786 | 0.74 | KMT2A (1.00) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007006-A1 | TRIAZOLO- AND PYRAZOLOQUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITOR | H. LUNDBECK A/S (DK) | 2012-01-19 | — | — | WO | disclosed |