SCHEMBL10100097

SCHEMBL10100097

Cc1ccc(-c2cc(CC(=O)OCC3C4C=CC(C4)C3COC(=O)Cc3cc(-c4ccc(C)s4)sc3-c3ccc(C)s3)c(-c3ccc(C)s3)s2)s1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10100096 0.92 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL10100094 0.84 TP53 (0.31) TP53MAPT
SCHEMBL10100088 0.80 KDM4E (0.36) MAPT
SCHEMBL10100093 0.78
SCHEMBL10100095 0.77
SCHEMBL10100105 0.71
SCHEMBL15695230 0.68 TP53 (0.33) TP53MAPT
SCHEMBL14319040 0.68 HDAC1 (0.36) MAPT
SCHEMBL2744940 0.67 HDAC1 (0.34) MAPT
SCHEMBL26509198 0.66 DAO (0.47) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120196078-A1 CONJUGATED POLYMER FIBER, PREPARATION AND USE THEREOF SOTZING GREGORY A (US) 2012-08-02 US disclosed
US-8178629-B2 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT (US) 2012-05-15 US disclosed
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US disclosed
US-20070089845-A1 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT 2007-04-26 US disclosed