SCHEMBL10100866

SCHEMBL10100866

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc(C(C)(C)c2ccc(C(C)(C)c3ccc(-n4c5ccc(C)cc5c5cc(C)ccc54)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
POLB P06746 2/20 0.37
NR1H4 Q96RI1 3/20 0.36
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
USP14 P54578 1/20 0.34
KIF11 P52732 1/20 0.34
ESR1 P03372 2/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
CYP3A4 P08684 1/20 0.33
AR P10275 1/20 0.33
HPGD P15428 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR6 P50406 1/20 0.33
ESRRG P62508 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17194088 1.00 TSHR (0.39) TSHRPOLBNR1H4KDM4EGAA
SCHEMBL13026249 0.91 TSHR (0.50) TSHRPOLBNR1H4KDM4EGAA
SCHEMBL24029988 0.91 CNR1 (0.40) TSHRNR1H4KDM4EGAAMAPT
SCHEMBL13589264 0.89 TSHR (0.35) TSHRPOLBNR1H4KDM4EGAA
SCHEMBL13589174 0.88 POLB (0.33) TSHRPOLBNR1H4KDM4EGAA
SCHEMBL13589280 0.88 TSHR (0.36) TSHRPOLBNR1H4KDM4EGAA
SCHEMBL13589242 0.88 TSHR (0.36) TSHRPOLBNR1H4KDM4EGAA
SCHEMBL24030013 0.87 KDM4E (0.45) NR1H4KDM4EMAPTKIF11ESR1
SCHEMBL15025823 0.87 POLB (0.44) TSHRPOLBKDM4EGAAMAPT
SCHEMBL2719134 0.85 TSHR (0.44) TSHRPOLBNR1H4KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed