Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18104855 | 0.80 | FFAR1 (0.42) | GRM5KCNH2FFAR1 | |
| Methyl Alcohol SCHEMBL28902013 | 0.78 | GRM5 (0.67) | GRM5KCNH2CYP1A2FFAR1 | |
| SCHEMBL352291 | 0.78 | GRM5 (0.65) | GRM5KCNH2CYP1A2 | |
| SCHEMBL1940910 | 0.78 | GRM5 (0.52) | GRM5KCNH2CYP1A2FFAR1 | |
| SCHEMBL30107570 | 0.77 | GRM5 (0.55) | GRM5KCNH2CYP1A2 | |
| SCHEMBL2160771 | 0.77 | GRM5 (0.55) | GRM5KCNH2CYP1A2 | |
| SCHEMBL408472 | 0.74 | GRM5 (0.49) | GRM5KCNH2CYP1A2 | |
| SCHEMBL29610604 | 0.74 | — | — | |
| SCHEMBL5560365 | 0.74 | — | — | |
| SCHEMBL4927688 | 0.73 | GRM5 (0.55) | GRM5KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009111337-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2009-09-11 | — | — | WO | disclosed |