Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271699 | 0.90 | GSK3B (0.73) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL88142 | 0.88 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL497122 | 0.87 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3805256 | 0.87 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL14063635 | 0.86 | GSK3B (0.65) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8273479 | 0.86 | GSK3B (0.74) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4030996 | 0.86 | GSK3B (0.65) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4030991 | 0.86 | GSK3B (0.65) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8271694 | 0.85 | GSK3B (0.56) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4031040 | 0.85 | GSK3B (0.73) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106045-B2 | 2-morpholino-4-pyrimidone compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-8106045-B2 | 2-morpholino-4-pyrimidone compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090124618-A1 | 2-MORPHOLINO-4-PYRIMIDONE COMPOUND | MITSUBISHI PHARMA CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
| US-20090124618-A1 | 2-MORPHOLINO-4-PYRIMIDONE COMPOUND | MITSUBISHI PHARMA CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124618-A1 | 2-MORPHOLINO-4-PYRIMIDONE COMPOUND | MAPT, PSEN1, PSEN2 | GSK3B 459/4885CYP2D6 3161/4885CYP1A2 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.