Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | CCR3 | P51677 | 4/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1010471 | 0.99 | SCD (0.50) | SCDHRH1CCR3PDE9A | |
| Hydrochloric Acid SCHEMBL1009830 | 0.86 | GPR6 (0.38) | SCDHRH1CCR3 | |
| Hydrochloric Acid SCHEMBL1010561 | 0.84 | SCD (0.45) | SCD | |
| SCHEMBL9902292 | 0.74 | SCD (0.55) | SCDHRH1CCR3 | |
| SCHEMBL1231590 | 0.74 | SCD (0.50) | SCD | |
| SCHEMBL2636999 | 0.74 | SCD (0.52) | SCDHRH1CCR3 | |
| SCHEMBL2636799 | 0.73 | SCD (0.54) | SCDHRH1CCR3 | |
| SCHEMBL69686 | 0.73 | SCD (0.51) | SCD | |
| Hydrochloric Acid SCHEMBL1009786 | 0.73 | SCD (0.39) | SCD | |
| Hydrochloric Acid SCHEMBL69924 | 0.72 | SCD (0.50) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | disclosed |