SCHEMBL10109264

SCHEMBL10109264

c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccc(N(c5ccc(-c6ccccc6)cc5)c5ccc(C6CCCCC6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
RAF1 P04049 1/20 0.43
SLC18A3 Q16572 1/20 0.41
DHODH Q02127 1/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
NOTUM Q6P988 2/20 0.41
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
TNK2 Q07912 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR5 Q9H228 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23680201 0.98 NPC1 (0.49) NPC1RAB9ARAF1SLC18A3DHODH
SCHEMBL19090026 0.98 NPC1 (0.49) NPC1RAB9ARAF1SLC18A3DHODH
SCHEMBL10029847 0.98 NPC1 (0.49) NPC1RAB9ARAF1SLC18A3DHODH
SCHEMBL23680203 0.98 NPC1 (0.49) NPC1RAB9ARAF1SLC18A3DHODH
SCHEMBL10029826 0.98 NPC1 (0.49) NPC1RAB9ARAF1SLC18A3DHODH
SCHEMBL21173567 0.93 SLC18A3 (0.46) SLC18A3MAPTTDP1KMT2AKDM4E
SCHEMBL20924752 0.93 SLC18A3 (0.46) SLC18A3MAPTTDP1KMT2AKDM4E
SCHEMBL22618672 0.93 SLC18A3 (0.46) SLC18A3MAPTTDP1KMT2AKDM4E
SCHEMBL22522816 0.93 SLC18A3 (0.46) SLC18A3MAPTTDP1KMT2AKDM4E
SCHEMBL17811576 0.92 NPC1 (0.44) NPC1RAB9ARAF1SLC18A3DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed