SCHEMBL10109359

SCHEMBL10109359

Cc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccc(-c5ccc(N(c6ccccc6)c6ccc(C)cc6)cc5)cc4)c4ccc(-c5ccc(N(c6ccccc6)c6ccc(-c7ccc(-c8ccccc8)s7)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.56
HSD17B1 P14061 7/20 0.45
HSD17B2 P37059 7/20 0.45
MAPT P10636 2/20 0.45
RXFP1 Q9HBX9 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
NQO2 P16083 2/20 0.41
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051482 1.00 APP (0.56) APPHSD17B1HSD17B2MAPTRXFP1
SCHEMBL13125840 0.98 APP (0.54) APPHSD17B1HSD17B2MAPTRXFP1
SCHEMBL13020740 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL13020756 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL15591841 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL13125869 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL13020762 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL10109304 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL13125854 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1
SCHEMBL13020757 0.91 APP (0.65) APPHSD17B1HSD17B2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed