Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16145854 | 0.83 | MAPK1 (0.30) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL944732 | 0.75 | POLB (0.34) | LMNA | |
| SCHEMBL15739 | 0.69 | MAPK1 (0.31) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL1302443 | 0.69 | GRM2 (0.30) | — | |
| SCHEMBL28766771 | 0.69 | — | — | |
| SCHEMBL466217 | 0.69 | — | — | |
| SCHEMBL3092761 | 0.68 | CYP2C19 (0.31) | CYP2C19 | |
| SCHEMBL467512 | 0.67 | SLC1A3 (0.31) | — | |
| SCHEMBL9717702 | 0.65 | — | — | |
| SCHEMBL6226499 | 0.64 | SLC1A3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268697-A1 | EPOXY-IMIDAZOLE CATALYSTS USEFUL FOR POWDER COATING APPLICATIONS | Dow Global Technologies Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009129088-A1 | EPOXY-IMIDAZOLE CATALYSTS USEFUL FOR POWDER COATING APPLICATIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-10-22 | — | — | WO | disclosed |