SCHEMBL10110857

SCHEMBL10110857

CC(C)(C)NCCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.65
▸ PRSS1 P07477 1/20 0.65
▸ PRSS2 P07478 1/20 0.65
▸ PRSS3 P35030 1/20 0.65
▸ TPSAB1 Q15661 1/20 0.65
▸ PKM P14618 3/20 0.61
▸ FOLH1 Q04609 5/20 0.59
▸ TDP1 Q9NUW8 5/20 0.56
▸ HSP90AB1 P08238 1/20 0.53
▸ CA12 O43570 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ ABL1 P00519 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ IDE P14735 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ RIN1 Q13671 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18025039 0.96 F2 (0.67) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL10110855 0.96 F2 (0.67) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL15216220 0.90 F2 (0.73) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL19017236 0.90 F2 (0.73) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL4968230 0.90 F2 (0.73) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL19751698 0.90 F2 (0.73) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL10126107 0.90 F2 (0.69) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL16602282 0.90 F2 (0.71) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL18612883 0.89 F2 (0.67) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL16075601 0.89 F2 (0.67) F2PRSS1PRSS2PRSS3TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9333232-B2 Methods for treating papilloma virus infection NANOVIR LLC (US) 2016-05-10 — — US disclosed
US-9290551-B2 Compounds for treating papilloma virus infection NANOVIR LLC (US) 2016-03-22 — — US disclosed
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-08-27 — — US disclosed
US-8993609-B2 Compounds for treating papilloma virus infection NANOVIR, LLC (US) 2015-03-31 — — US disclosed
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION NANOVIR, LLC (US) 2012-09-06 — — US disclosed
US-8119677-B2 Polyamides containing amino butyric acid-based building blocks NANOVIR, LLC (US) 2012-02-21 — — US disclosed
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2010-01-21 — — US disclosed
US-20090306164-A1 Methods for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2009-12-10 — — US disclosed
US-7589171-B2 Polyamides for treating human papilloma virus NANOVIR, LLC (US) 2009-09-15 — — US disclosed
US-20070293417-A1 Polyamides for treating human papilloma virus NANOVIR, LLC 2007-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 F2 4719/4885PRSS1 317/4885PRSS2 652/4885
US-20090306164-A1 Methods for Treating Papilloma Virus Infection POLI, VHL, TLR3 F2 4324/4885PRSS1 538/4885PRSS2 709/4885
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 F2 4719/4885PRSS1 317/4885PRSS2 652/4885
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection POLI, PMAIP1, TLR3 F2 4798/4885PRSS1 384/4885PRSS2 909/4885
US-20070293417-A1 Polyamides for treating human papilloma virus POLI, PARG, PARN F2 4845/4885PRSS1 783/4885PRSS2 1395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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