Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009803 | 0.90 | GRM5 (0.46) | GRM5GPR84CASR | |
| SCHEMBL4079520 | 0.82 | GRM5 (0.49) | GRM5 | |
| SCHEMBL1011301 | 0.81 | GRM5 (0.57) | GRM5 | |
| SCHEMBL1009219 | 0.80 | GRM5 (0.41) | GRM5 | |
| SCHEMBL1010885 | 0.78 | GRM5 (0.43) | GRM5CASR | |
| SCHEMBL1009714 | 0.78 | GRM5 (0.41) | GRM5GPR84 | |
| SCHEMBL3816795 | 0.77 | KMT2A (0.40) | GRM5GPR84 | |
| SCHEMBL1011333 | 0.76 | GRM5 (0.41) | GRM5 | |
| SCHEMBL1010806 | 0.74 | GRM5 (0.41) | GRM5GPR84 | |
| SCHEMBL1010801 | 0.74 | GRM5 (0.47) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054416-B1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO KGAA (DE) | 2011-01-05 | — | — | EP | disclosed |