Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250705 | 0.84 | HDAC3 (0.50) | P2RY12ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL12723444 | 0.76 | ACACB (0.40) | P2RY12ALDH1A1GAA | |
| SCHEMBL8243063 | 0.74 | P2RY12 (0.45) | NR1D1P2RY12PKMCNR2HDAC3 | |
| SCHEMBL1012011 | 0.74 | P2RY12 (0.42) | P2RY12ALDH1A1GAA | |
| SCHEMBL8251602 | 0.72 | P2RY12 (0.42) | P2RY12ALDH1A1KDM4EGAANPSR1 | |
| SCHEMBL1012529 | 0.72 | ATM (0.44) | P2RY12TGM2ALDH1A1LMNAGAA | |
| SCHEMBL1010754 | 0.70 | PCSK9 (0.38) | P2RY12HTTSMN1; SMN2 | |
| SCHEMBL12939752 | 0.69 | KMT2A (0.58) | P2RY12ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL1011840 | 0.68 | HDAC3 (0.56) | ALDH1A1LMNAGAATSHRSMN1; SMN2 | |
| SCHEMBL1011967 | 0.67 | HDAC3 (0.55) | ALDH1A1LMNAGAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932246-B2 | Histone deacetylase inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2011-04-26 | — | — | US | disclosed |
| EP-1881977-B1 | HISTONE DEACETYLASE INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2011-01-05 | — | — | EP | disclosed |
| US-20100152155-A1 | Histone Deacetylase Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2010-06-17 | — | — | US | disclosed |
| EP-1881977-A1 | HISTONE DEACETYLASE INHIBITORS | Chroma Therapeutics Limited (GB) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006123121-A1 | HISTONE DEACETYLASE INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152155-A1 | Histone Deacetylase Inhibitors | HDAC1, HDAC2, HDAC11 | NR1D1 650/4885CNR1 4009/4885P2RY12 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.