Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1011364

CCOc1cc(C=C2CCN(C(=O)Nc3cccnc3)CC2)cc(Oc2ccc(C(F)(F)F)cn2)c1.O=C(O)C(F)(F)F

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.75
CYP2D6 P10635 4/20 0.75
FAAH O00519 16/20 0.58
HTR2A P28223 2/20 0.58
HTR2C P28335 2/20 0.58
GABRA1 P14867 1/20 0.58
ADRA2C P18825 1/20 0.58
CNR1 P21554 1/20 0.58
CNR2 P34972 1/20 0.58
HTR2B P41595 1/20 0.58
TMEM97 Q5BJF2 1/20 0.58
SIGMAR1 Q99720 1/20 0.58
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010716 0.97 CYP3A4 (0.79) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1011396 0.88 CYP3A4 (0.81) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1010303 0.88 CYP3A4 (0.83) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1010755 0.87 CYP3A4 (0.81) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1011836 0.86 CYP3A4 (1.00) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1010896 0.82 CYP3A4 (0.89) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1011327 0.82 CYP3A4 (0.91) CYP3A4CYP2D6FAAHHTR2AHTR2C
Trifluoroacetic Acid SCHEMBL1012131 0.82 CYP3A4 (0.80) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1010134 0.81 CYP3A4 (0.75) CYP3A4CYP2D6FAAHHTR2AHTR2C
SCHEMBL1009793 0.81 CYP3A4 (0.76) CYP3A4CYP2D6FAAHHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2076508-B1 BIARYL ETHER UREA COMPOUNDS PFIZER PROD INC (US) 2011-01-05 EP disclosed