Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10134100 | 1.00 | TP53 (0.38) | TP53SMN1; SMN2KMT2AF10GAK | |
| SCHEMBL14418495 | 1.00 | TP53 (0.38) | TP53SMN1; SMN2KMT2AF10GAK | |
| SCHEMBL13204298 | 1.00 | TP53 (0.38) | TP53SMN1; SMN2KMT2AF10GAK | |
| SCHEMBL14424079 | 0.88 | TP53 (0.42) | TP53SMN1; SMN2KMT2AF10GAK | |
| SCHEMBL10114451 | 0.88 | TP53 (0.42) | TP53SMN1; SMN2KMT2AF10GAK | |
| SCHEMBL10134414 | 0.88 | TP53 (0.42) | TP53SMN1; SMN2KMT2AF10GAK | |
| SCHEMBL17090227 | 0.82 | LRRK2 (0.35) | KCNH2GRIA4TRPV1 | |
| SCHEMBL10114745 | 0.78 | HRH3 (0.46) | KMT2AGAKMAPTGSK3BKCNH2 | |
| SCHEMBL10114405 | 0.78 | HRH3 (0.46) | KMT2AGAKMAPTGSK3BKCNH2 | |
| SCHEMBL10133518 | 0.78 | MAPT (0.41) | TP53SMN1; SMN2KMT2AMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | TP53 4417/4885SMN1; SMN2 2197/4885KMT2A 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.