SCHEMBL10114980

C=C(C)C(=O)OCCCC[SiH2]O[Si](C)(C)CCCC[Si](O[Si](C)(C)CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)CCCCCCC)(O[Si](C)(C)CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)CCCCCCC)O[Si](C)(C)CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)CCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	2/20	0.48

▸	POLB	P06746	1/20	0.31

▸	APEX1	P27695	1/20	0.31

▸	HTT	P42858	1/20	0.31

▸	TDP1	Q9NUW8	1/20	0.31

▸	THRB	P10828	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10115124	0.95	TSHR (0.38)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL14723949	0.90	TSHR (0.39)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL12002706	0.86	TSHR (0.40)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL10114962	0.83	—	—
SCHEMBL31299544	0.81	TSHR (0.69)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL433972	0.80	TSHR (0.44)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL10115076	0.80	TSHR (0.45)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL10115118	0.80	—	—
SCHEMBL393193	0.79	TSHR (0.57)	TSHRPOLBAPEX1HTTTDP1
SCHEMBL395576	0.79	TSHR (0.57)	TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8383234-B2	Charging member, process cartridge, and electrophotographic apparatus	CANON KABUSHIKI KAISHA (JP)	2013-02-26	—	—	US	disclosed
US-20120141162-A1	CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS	CANON KABUSHIKI KAISHA (JP)	2012-06-07	—	—	US	disclosed