Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 3/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182576 | 0.84 | AAK1 (0.37) | AAK1ALPLPAX8 | |
| SCHEMBL19334050 | 0.84 | SSTR4 (0.33) | AAK1SSTR4 | |
| SCHEMBL18731533 | 0.79 | SSTR4 (0.39) | TSPOSSTR4ALDH1A1HTTPAX8 | |
| SCHEMBL21334068 | 0.78 | AAK1 (0.31) | AAK1PAX8 | |
| SCHEMBL18829257 | 0.76 | AAK1 (0.43) | AAK1HTT | |
| SCHEMBL16270845 | 0.75 | HDAC1 (0.35) | AAK1 | |
| SCHEMBL19333714 | 0.75 | AAK1 (0.34) | AAK1FPR2SSTR4 | |
| SCHEMBL18730955 | 0.74 | SSTR4 (0.34) | AAK1ALPLTSPOSSTR4ALDH1A1 | |
| SCHEMBL10182271 | 0.74 | KMT2A (0.42) | AAK1ALPLFPR2ALDH1A1 | |
| SCHEMBL2617383 | 0.74 | KMT2A (0.42) | AAK1ALPLFPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087976-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-06-28 | — | — | WO | disclosed |