Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.42 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | HINT1 | P49773 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786908 | 1.00 | MEN1 (0.53) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL309414 | 0.87 | MEN1 (0.54) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10117981 | 0.83 | MEN1 (0.56) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10117982 | 0.81 | POLB (0.53) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL309885 | 0.79 | MEN1 (0.56) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL13243123 | 0.79 | MEN1 (0.56) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10117980 | 0.79 | MEN1 (0.56) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL13242389 | 0.79 | POLB (0.56) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10118025 | 0.79 | MEN1 (0.59) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL14274473 | 0.78 | MEN1 (0.53) | MEN1USP2POLBKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093380-B2 | Viricides, antitumor agents, anticancer agents | PHARMASSET, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093380-B2 | Viricides, antitumor agents, anticancer agents | PHARMASSET, INC. (US) | 2012-01-10 | — | — | US | disclosed |