SCHEMBL10119221

SCHEMBL10119221

C=C(C)C(=O)OCCN(CCOC(=O)C(=C)C)c1ccc(/N=N/c2c(C#N)cc([N+](=O)[O-])cc2C#N)c(NC(C)=O)c1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.36
HTT P42858 2/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 5/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 3/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP19A1 P11511 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622516 0.86 HTT (0.44) RECQLHTTGAASMN1; SMN2GLA
SCHEMBL622515 0.86 HTT (0.44) RECQLHTTGAASMN1; SMN2GLA
SCHEMBL10119239 0.85 MAPT (0.31) MAPT
SCHEMBL29363175 0.84 RECQL (0.41) RECQLHTTGAASMN1; SMN2GLA
SCHEMBL11222989 0.84 RECQL (0.41) RECQLHTTGAASMN1; SMN2GLA
SCHEMBL11223012 0.84 RECQL (0.41) RECQLHTTGAASMN1; SMN2GLA
SCHEMBL22004961 0.82 MAPT (0.49) RECQLHTTGAASMN1; SMN2GLA
SCHEMBL9589087 0.81 RECQL (0.43) RECQLHTTGAASMN1; SMN2MAPT
SCHEMBL9589094 0.81 RECQL (0.43) RECQLHTTGAASMN1; SMN2MAPT
SCHEMBL17122034 0.81 MAPT (0.37) RECQLHTTGAASMN1; SMN2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308744-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-06-04 US disclosed
US-9868803-B2 Colored polymer particles for electrophoretic displays MERCK PATENT GMBH (DE) 2018-01-16 US disclosed
US-9868803-B2 Colored polymer particles for electrophoretic displays MERCK PATENT GMBH (DE) 2018-01-16 US disclosed
US-9494808-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-15 US disclosed
US-9494808-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-15 US disclosed
EP-2850489-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2016-11-09 EP disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 US disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 US disclosed
US-9383621-B2 Electrophoretic fluids MERCK PATENT GMBH (DE) 2016-07-05 US disclosed
US-9383621-B2 Electrophoretic fluids MERCK PATENT GMBH (DE) 2016-07-05 US disclosed
US-20150129817-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2015-05-14 US disclosed
US-20150099119-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2015-04-09 US disclosed
US-20150099119-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2015-04-09 US disclosed
WO-2014198375-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2014-12-18 WO disclosed
WO-2014198373-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2014-12-18 WO disclosed
US-20140313567-A1 ELECTROPHORETIC FLUIDS E INK CORPORATION 2014-10-23 US disclosed
US-20140313567-A1 ELECTROPHORETIC FLUIDS E INK CORPORATION 2014-10-23 US disclosed
US-20130208344-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130208344-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
WO-2012019704-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed