Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622515 | 0.87 | HTT (0.44) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL622516 | 0.87 | HTT (0.44) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL22004959 | 0.86 | MAPT (0.39) | NPC1MAPTRAB9ASTK4HTT | |
| SCHEMBL626835 | 0.86 | MAPT (0.33) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL626834 | 0.86 | MAPT (0.33) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL13475206 | 0.82 | HTT (0.34) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL622281 | 0.81 | HTT (0.41) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL622280 | 0.81 | HTT (0.41) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL12344193 | 0.79 | MAPT (0.37) | NPC1MAPTTDP1MEN1LMNA | |
| SCHEMBL7768502 | 0.77 | CA12 (0.36) | MAPTMEN1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019704-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |