Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627822 | 0.83 | HPGD (0.53) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL30540817 | 0.83 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL1331823 | 0.81 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL30715039 | 0.79 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL26917374 | 0.79 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL26917372 | 0.79 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL25070622 | 0.77 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL26917240 | 0.77 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL26917236 | 0.77 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL20621430 | 0.77 | HPGD (0.41) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |