Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120102 | 0.84 | GAA (0.44) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL15179285 | 0.84 | GAA (0.46) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL14963797 | 0.84 | GAA (0.57) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL14963861 | 0.84 | GAA (0.50) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL10120321 | 0.84 | GAA (0.43) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL15179298 | 0.83 | GAA (0.48) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL15179381 | 0.83 | GAA (0.45) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL10120318 | 0.83 | GAA (0.45) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL10120306 | 0.83 | GAA (0.42) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL10048858 | 0.83 | GAA (0.49) | KDM4EGAAALDH1A1HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |