Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179287 | 0.88 | KDM4E (0.45) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL10120315 | 0.83 | MAPT (0.49) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL10120623 | 0.83 | MAPT (0.47) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL10120313 | 0.82 | MAPT (0.46) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL15179491 | 0.81 | MAPT (0.46) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL10120435 | 0.81 | MAPT (0.45) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL15179332 | 0.81 | MAPT (0.45) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL15179292 | 0.79 | GAA (0.46) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL15179358 | 0.79 | MAPT (0.46) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL10120309 | 0.79 | GAA (0.46) | MAPTTP53GAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |