Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526262 | 0.93 | BACE1 (0.49) | BACE1 | |
| SCHEMBL7531630 | 0.89 | BACE1 (0.56) | BACE1 | |
| SCHEMBL7524320 | 0.88 | BACE1 (0.41) | BACE1 | |
| SCHEMBL12504734 | 0.88 | BACE1 (0.50) | BACE1 | |
| SCHEMBL7539352 | 0.84 | BACE1 (0.55) | BACE1 | |
| SCHEMBL7524335 | 0.83 | BACE1 (0.50) | BACE1 | |
| SCHEMBL2965350 | 0.83 | BACE1 (0.54) | BACE1 | |
| SCHEMBL7526245 | 0.82 | BACE1 (0.43) | BACE1 | |
| SCHEMBL8266828 | 0.80 | BACE1 (0.44) | BACE1 | |
| SCHEMBL8290207 | 0.80 | BACE1 (0.39) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178513-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |