Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723435 | 0.70 | — | — | |
| SCHEMBL9606 | 0.67 | FFAR3 (0.40) | FFAR3 | |
| SCHEMBL3670104 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL4398568 | 0.62 | — | — | |
| SCHEMBL5185822 | 0.61 | CYP3A4 (0.31) | — | |
| SCHEMBL12986569 | 0.61 | CYP19A1 (0.41) | FFAR3 | |
| SCHEMBL21230083 | 0.60 | — | — | |
| SCHEMBL1655866 | 0.60 | FFAR3 (0.32) | FFAR3 | |
| SCHEMBL6581060 | 0.59 | FFAR3 (0.35) | FFAR3 | |
| SCHEMBL9804280 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526771-B1 | Inhibitors of bruton's tyrosine kinase | PHARMACYCLICS LLC (US) | 2016-11-30 | — | — | EP | claimed |
| EP-2511257-B1 | Composition comprising an alpha ketoamide compound as cysteine protease inhibitor | VIROBAY INC (US) | 2015-06-17 | — | — | EP | claimed |
| EP-1656372-B1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS FOR USE IN THE TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES | RIGEL PHARMACEUTICALS INC (US) | 2013-04-10 | — | — | EP | claimed |
| EP-1824489-B1 | STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS INC (US) | 2011-01-05 | — | — | EP | claimed |