Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.49 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10124482 | 0.90 | PIK3CD (0.57) | PIK3CDPIK3CB | |
| SCHEMBL10124462 | 0.90 | PIK3CD (0.55) | PIK3CDPIK3CB | |
| SCHEMBL10124487 | 0.89 | PIK3CD (0.57) | PIK3CDPIK3CB | |
| SCHEMBL10124471 | 0.87 | PIK3CD (0.53) | PIK3CDPIK3CB | |
| SCHEMBL10124492 | 0.87 | PIK3CD (0.58) | PIK3CDPIK3CB | |
| SCHEMBL10124478 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CBCCNCCDK8 | |
| SCHEMBL10154266 | 0.83 | PIK3CB (0.68) | PIK3CDPIK3CB | |
| SCHEMBL10124531 | 0.82 | PIK3CD (0.58) | PIK3CDPIK3CB | |
| SCHEMBL10124535 | 0.81 | PIK3CD (0.59) | PIK3CDPIK3CB | |
| SCHEMBL10124520 | 0.81 | PIK3CD (0.56) | PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165309-A1 | HETERO RING DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20120165309-A1 | HETERO RING DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165309-A1 | HETERO RING DERIVATIVE | IL2, PIK3R2, IL2RA | PIK3CD 7/4885PIK3CB 13/4885EPHX2 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.