SCHEMBL1012558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1014738	0.85	HDAC3 (0.80)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL1011552	0.84	HDAC3 (0.79)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL8248804	0.83	HDAC3 (1.00)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL1080350	0.79	HDAC3 (0.67)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL1011661	0.77	HDAC3 (0.72)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL1013678	0.73	HDAC3 (0.74)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL8203125	0.72	ACACB (0.50)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL1010846	0.72	HDAC3 (0.71)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL12723461	0.71	ACACB (0.50)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL8205621	0.71	ACACB (0.49)	HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.