Sugi Predict

Sugi Predict / Compounds / SCHEMBL10127732

SCHEMBL10127732

SCHEMBL10127732

CC(C)c1ccc2c(c1)c1cc(C(C)C)ccc1n2-c1ccc(-c2nnc3c4ccccc4c4ccccc4n23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.44
▸ RORA P35398 1/20 0.38
▸ RORC P51449 1/20 0.38
▸ RORB Q92753 1/20 0.38
▸ UCHL3 P15374 1/20 0.35
▸ KDM4E B2RXH2 3/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ TP53 P04637 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.33
▸ CASR P41180 1/20 0.33
▸ DHFR P00374 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ TYMS P04818 1/20 0.33
▸ TUBB4A P04350 1/20 0.32
▸ TUBB P07437 1/20 0.32
▸ TUBA3C P0DPH7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10127806 1.00 POLB (0.44) POLBRORARORCRORBUCHL3
SCHEMBL10127741 0.89 POLB (0.41) POLBRORARORCRORBUCHL3
SCHEMBL10127805 0.89 POLB (0.41) POLBRORARORCRORBUCHL3
SCHEMBL10127717 0.86 POLB (0.47) POLBRORARORCRORBKDM4E
SCHEMBL10127718 0.86 POLB (0.47) POLBRORARORCRORBKDM4E
SCHEMBL10127787 0.86 POLB (0.47) POLBRORARORCRORBKDM4E
SCHEMBL516019 0.86 POLB (0.52) POLBKDM4EATML3MBTL1ALDH1A1
SCHEMBL10128670 0.85 POLB (0.41) POLBRORARORCRORBKDM4E
SCHEMBL10128489 0.85 POLB (0.41) POLBRORARORCRORBKDM4E
SCHEMBL10127695 0.84 POLB (0.51) POLBKDM4EATML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device HTR3D, KCNQ4, KCNQ3 POLB 3317/4885RORA 1031/4885RORC 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.