Sugi Predict

Sugi Predict / Compounds / SCHEMBL10128632

SCHEMBL10128632

SCHEMBL10128632

Ic1cccc2c(-c3nnc4c5ccccc5c5ccccc5n34)cccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.48
▸ PDE2A O00408 8/20 0.39
▸ PDE10A Q9Y233 7/20 0.39
▸ TP53 P04637 3/20 0.34
▸ MAPT P10636 1/20 0.34
▸ MAOA P21397 2/20 0.34
▸ MAOB P27338 1/20 0.34
▸ HSD11B1 P28845 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TUBB4A P04350 1/20 0.33
▸ TUBB P07437 1/20 0.33
▸ TUBA3C P0DPH7 1/20 0.33
▸ TUBA1B P68363 1/20 0.33
▸ TUBA4A P68366 1/20 0.33
▸ TUBB4B P68371 1/20 0.33
▸ TUBB3 Q13509 1/20 0.33
▸ TUBB2A Q13885 1/20 0.33
▸ TUBB8 Q3ZCM7 1/20 0.33
▸ TUBA3E Q6PEY2 1/20 0.33
▸ TUBA1A Q71U36 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128631 0.93 POLB (0.46) POLBPDE2APDE10ATP53MAPT
SCHEMBL10128628 0.91 POLB (0.47) POLBPDE2APDE10ATP53MAPT
SCHEMBL10128649 0.88 POLB (0.45) POLBPDE2APDE10ATP53MAPT
SCHEMBL10128652 0.83 POLB (0.49) POLBTP53MAPTMAOAHPGD
SCHEMBL10128443 0.82 POLB (0.48) POLBPDE2APDE10ATP53MAOA
SCHEMBL10127690 0.81 POLB (0.47) POLBPDE2APDE10ATP53MAPT
SCHEMBL10128650 0.79 POLB (0.45) POLBPDE2APDE10ATP53MAPT
SCHEMBL10128440 0.79 POLB (0.47) POLBPDE2APDE10AMAOAMAOB
SCHEMBL10128447 0.78 POLB (0.46) POLBPDE2APDE10AMAOAMAOB
SCHEMBL10127685 0.78 POLB (0.46) POLBPDE2APDE10ATP53MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
WO-2012017842-A1 TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 — — WO disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device HTR3D, KCNQ4, KCNQ3 POLB 3317/4885PDE2A 3339/4885PDE10A 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.