⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398132 | 0.84 | — | — | |
| SCHEMBL3439955 | 0.81 | — | — | |
| SCHEMBL16094855 | 0.80 | — | — | |
| SCHEMBL16094969 | 0.78 | — | — | |
| SCHEMBL16094968 | 0.78 | — | — | |
| SCHEMBL622521 | 0.71 | — | — | |
| SCHEMBL1823248 | 0.70 | — | — | |
| SCHEMBL1275816 | 0.69 | — | — | |
| SCHEMBL16397899 | 0.69 | — | — | |
| SCHEMBL16095276 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542692-B1 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | AMGEN INC (US) | 2011-01-05 | — | — | EP | claimed |
| EP-2270006-A1 | Pyridazine derivatives useful as vanilloid receptor ligands | Amgen, Inc (US) | 2011-01-05 | — | — | EP | claimed |
| US-7524874-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-04-28 | — | — | US | claimed |
| US-7439360-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-10-21 | — | — | US | claimed |
| US-7396831-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-07-08 | — | — | US | claimed |
| US-7390907-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-06-24 | — | — | US | claimed |
| US-7332511-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-02-19 | — | — | US | claimed |
| EP-1780196-A2 | Pyridine derivatives for use as vanilloid receptor ligands | Amgen, Inc (US) | 2007-05-02 | — | — | EP | claimed |
| US-20070093455-A1 | 10-substituted tetracyclines and methods of use thereof | PARATEK PHARMACEUTICALS, INC. | 2007-04-26 | — | — | US | claimed |
| US-7148221-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2006-12-12 | — | — | US | claimed |
| WO-2003049702-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2003-06-19 | — | — | WO | claimed |
| CN-1056612-C | Process for epoxidation of prochiral olefins, catalyst for use in the process | SMITHKLINE BEECHAM PLC (GB) | 2000-09-20 | — | — | CN | claimed |
| US-5916975-A | Process for epoxidising prochiral olefins and a catalyst therefor and intermediates for making the catalyst | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-06-29 | — | — | US | claimed |
| CN-1043425-C | Novel compounds and process | SMITHKLINE BEECHAM PLC (GB) | 1999-05-19 | — | — | CN | claimed |
| US-5616750-A | Compounds and process | SMITHKLINE BEECHAM PLC (GB) | 1997-04-01 | — | — | US | claimed |
| CN-1145623-A | Process for epoxidation of prochiral olefins, catalyst for use in the process and intermediates for making the catalyst | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | CN | claimed |
| EP-0741731-A1 | PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST | SMITHKLINE BEECHAM PLC (GB) | 1996-11-13 | — | — | EP | claimed |
| EP-0655950-B1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1996-10-23 | — | — | EP | claimed |
| WO-1995021172-A1 | PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-08-10 | — | — | WO | claimed |
| CN-1098415-A | Novel compounds and method for making thereof | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | CN | claimed |