Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719971 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAKR1B1TSHRALDH1A1 | |
| SCHEMBL256747 | 0.91 | AVPR2 (0.42) | AVPR2AVPR1AAKR1B1TSHRALDH1A1 | |
| SCHEMBL6914750 | 0.89 | AVPR2 (0.44) | AVPR2AVPR1ATSHRALDH1A1MAPT | |
| SCHEMBL255993 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1ATSHRALDH1A1MAPT | |
| SCHEMBL21004008 | 0.75 | AVPR2 (0.45) | AVPR2AVPR1AAKR1B1TSHRALDH1A1 | |
| SCHEMBL8235255 | 0.75 | TSHR (0.43) | AVPR2AVPR1AAKR1B1TSHRALDH1A1 | |
| SCHEMBL8227129 | 0.75 | AVPR2 (0.46) | AVPR2AVPR1ATSHRPTGDR2CNR1 | |
| SCHEMBL8227138 | 0.75 | AVPR2 (0.51) | AVPR2AVPR1APTGDR2 | |
| SCHEMBL413351 | 0.73 | AVPR2 (0.57) | AVPR2AVPR1A | |
| SCHEMBL8235257 | 0.73 | AVPR2 (0.46) | AVPR2AVPR1ATSHRPTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035075-A1 | SUBSTITUTED PHENYLACETATE AND PHENYLPROPANE AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-22 | — | — | WO | disclosed |