Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRL | P40313 | 5/20 | 0.57 |
| ▸ | TMPRSS11D | O60235 | 4/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 15/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.56 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.56 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.56 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.56 |
| ▸ | PSMD11 | O00231 | 3/20 | 0.56 |
| ▸ | PSMD12 | O00232 | 3/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 3/20 | 0.56 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.56 |
| ▸ | PSMD3 | O43242 | 3/20 | 0.56 |
| ▸ | PSMC3 | P17980 | 3/20 | 0.56 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.56 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.56 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.56 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.56 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632714 | 0.93 | PSMB5 (0.64) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL2632717 | 0.92 | CTRL (0.56) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL2633293 | 0.91 | PSMB5 (0.59) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL2735645 | 0.86 | PSMB5 (0.61) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL10129801 | 0.85 | CTRL (0.53) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL2760024 | 0.85 | PSMB5 (0.50) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL13742992 | 0.85 | PSMB5 (0.75) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 | |
| SCHEMBL14208699 | 0.83 | PSMB5 (0.67) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL13932376 | 0.83 | PSMB5 (0.67) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL10086980 | 0.82 | CTRL (0.47) | CTRLTMPRSS11DPSMB5PSMB2PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101025-A1 | Compounds For Enzyme Inhibition | ONYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101025-A1 | Compounds For Enzyme Inhibition | ANPEP, DNPEP, CPN1 | CTRL 4/4885TMPRSS11D 320/4885PSMB5 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.