Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.53 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001423 | 0.92 | MCHR1 (0.50) | MCHR1KCNH2 | |
| SCHEMBL1005455 | 0.89 | MCHR1 (0.55) | MCHR1KCNH2 | |
| SCHEMBL1003458 | 0.88 | MCHR1 (0.56) | MCHR1KCNH2 | |
| SCHEMBL1001528 | 0.88 | MCHR1 (0.53) | MCHR1KCNH2PRCP | |
| SCHEMBL1005167 | 0.86 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL1003092 | 0.85 | MCHR1 (0.55) | MCHR1KCNH2 | |
| SCHEMBL1003280 | 0.84 | MCHR1 (0.57) | MCHR1KCNH2 | |
| SCHEMBL1001672 | 0.83 | MCHR1 (0.53) | MCHR1KCNH2 | |
| SCHEMBL1001674 | 0.83 | MCHR1 (0.53) | MCHR1KCNH2 | |
| SCHEMBL1003387 | 0.82 | MCHR1 (0.55) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272841-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING ANTAGONISTIC ACTIVITY ON MELANIN-CONCENTRATING HORMONE RECEPTOR | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |