⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19338007 | 1.00 | — | — | |
| SCHEMBL789897 | 1.00 | — | — | |
| SCHEMBL2791141 | 0.97 | — | — | |
| SCHEMBL2791140 | 0.97 | — | — | |
| SCHEMBL23191677 | 0.77 | — | — | |
| SCHEMBL722218 | 0.76 | — | — | |
| SCHEMBL11884356 | 0.76 | — | — | |
| SCHEMBL11884359 | 0.76 | — | — | |
| SCHEMBL11884351 | 0.76 | — | — | |
| SCHEMBL722217 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773577-A1 | TRICYCLIC ASK1 INHIBITORS | Terns, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| US-10919911-B2 | Tricyclic ASK1 inhibitors | Terns, Inc. (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190315767-A1 | TRICYCLIC ASK1 INHIBITORS | Terns, Inc. (US) | 2019-10-17 | — | — | US | disclosed |
| WO-2019200267-A1 | TRICYCLIC ASK1 INHIBITORS | Terns, Inc. (US) | 2019-10-17 | — | — | WO | disclosed |
| CN-108779108-A | 3- (2,3- dihydro -1H- indenes -5- bases) propanoic derivatives and their purposes as NRF2 conditioning agents | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-108137557-A | Nrf2 modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-06-08 | — | — | CN | disclosed |
| EP-2302010-B1 | Ink composition and method of producing a processed product of printed matter | FUJIFILM CORP (JP) | 2017-09-13 | — | — | EP | disclosed |
| WO-2017008743-A1 | AIE BIOPROBES EMITTING RED OR YELLOW FLUORESCENCE | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-01-19 | — | — | WO | disclosed |
| WO-2012009137-A1 | CRTH2 MODULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |
| WO-2007062230-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| EP-1757670-A2 | Organic electroluminescent element | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2007-02-28 | — | — | EP | disclosed |