⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149106 | 0.72 | — | — | |
| SCHEMBL18878593 | 0.62 | — | — | |
| SCHEMBL12532450 | 0.62 | — | — | |
| Ethylenediamine SCHEMBL6369522 | 0.56 | — | — | |
| SCHEMBL12054244 | 0.53 | — | — | |
| SCHEMBL1930146 | 0.53 | — | — | |
| SCHEMBL1276 | 0.53 | — | — | |
| SCHEMBL5609754 | 0.47 | — | — | |
| Phosphine SCHEMBL15477090 | 0.47 | — | — | |
| SCHEMBL4636818 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124636-B2 | Imidazolidinone derivatives as 11B-HSD1 inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090275573-A1 | Imidazolidinone Derivatives as 11B-HSD1 Inhibitors | HOFFMANN-LA ROCHE, INC. | 2009-11-05 | — | — | US | disclosed |